Biology

Weekly Byte

Abstract: “Long-term dietary intake influences the structure and activity of the trillions of microorganisms residing in the human gut, but it remains unclear how rapidly and...

Weekly Byte

Abstract: “The human genome encodes the blueprint of life, but the function of the vast majority of its nearly three billion bases is unknown. The Encyclopedia of DNA Elements (...

Weekly Byte

Abstract: “DNase I hypersensitive sites (DHSs) are markers of regulatory DNA and have underpinned the discovery of all classes of cis-regulatory elements including enhancers,...

Weekly Byte

Abstract: “The human genome encodes the blueprint of life, but the function of the vast majority of its nearly three billion bases is unknown. The Encyclopedia of DNA Elements (...

Weekly Byte

Abstract: “By characterizing the geographic and functional spectrum of human genetic variation, the 1000 Genomes Project aims to build a resource to help to understand the genetic contribution to...

Weekly Byte

Abstract: “We analysed primary breast cancers by genomic DNA copy number arrays, DNA methylation, exome sequencing, messenger RNA arrays, microRNA sequencing and reverse-phase...

Weekly Byte

“An integrated encyclopedia of DNA elements in the human genome,” by the ENCODE Project Consortium, Nature, 489(7414): 57-74, 6 September 2012.

[Authors' affiliations: 85 institutions...

Weekly Byte

“An integrated map of genetic variation from 1,092 human genomes,” by the 1000 Genomes Project, Nature, 491(7422): 56-65, 1 November 2012.  

[Authors' affiliations: 115 institutions...

Weekly Byte

[Authors' affiliations: Broad Institute, Cambridge, MA; MIT, Cambridge, MA; Harvard University, Cambridge, MA, Tsinghua University, Beijing, China; Columbia University, New York, NY; Rockefeller...

Weekly Byte

Abstract: “Since its introduction in 2001, MrBayes has grown in popularity as a software package for Bayesian phylogenetic inference using Markov chain Monte Carlo (MCMC) methods. With this note,...

Weekly Byte

Abstract: “To characterize somatic alterations in colorectal carcinoma, we conducted a genome-scale analysis of 276 samples, analysing exome sequence, DNA copy number, promoter methylation and...

Weekly Byte

Abstract:“We analysed primary breast cancers by genomic DNA copy number arrays, DNA methylation, exome sequencing, messenger RNA arrays, microRNA sequencing and reverse-phase...

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