Hot Paper in Psychiatry/Psychology

June 2014
“Childhood adversities increase the risk of psychosis: a meta-analysis of patient-control, prospective-, and cross-sectional studies,” by F. Varese, et al., Schizophrenia Bulletin, 38(4): 661-71, July 2012.

Abstract: “Evidence suggests that adverse experiences in childhood are associated with psychosis. To examine the association between childhood adversity and trauma (sexual abuse, physical abuse, emotional/psychological abuse, neglect, parental death, and bullying) and psychosis outcome, MEDLINE, EMBASE, PsychINFO, and Web of Science were searched from January 1980 through November 2011. We included prospective cohort studies, large-scale cross-sectional studies investigating the association between childhood adversity and psychotic symptoms or illness, case-control studies comparing the prevalence of adverse events between psychotic patients and controls using dichotomous or continuous measures, and case-control studies comparing the prevalence of psychotic symptoms between exposed and nonexposed subjects using dichotomous or continuous measures of adversity and psychosis. The analysis included 18 case-control studies (n = 2048 psychotic patients and 1856 nonpsychiatric controls), 10 prospective and quasi-prospective studies = 41 803) and 8 population-based cross-sectional studies (11 = 35 546). There were significant associations between adversity and psychosis across all research designs, with an overall effect of OR = 2.78 (95% CI = 2.34-3.31). The integration of the case-control studies indicated that patients with psychosis were 2.72 times more likely to have been exposed to childhood adversity than controls (95% CI = 1.90-3.88). The association between childhood adversity and psychosis was also significant in population-based cross-sectional studies (OR = 2.99 [95% CI = 2.12-4.20]) as well as in prospective and quasi-prospective studies (OR = 2.75 [95% CI = 2.17-3.47]). The estimated population attributable risk was 33% (16%-47%). These findings indicate that childhood adversity is strongly associated with increased risk for psychosis.”

This 2012 report from Schizophrenia Bulletin was cited 13 times in current journal articles indexed by Thomson Reuters during November-Dec 2013. Of papers published in the last two years in the main field of Psychiatry/Psychology, none collected a greater number of citations during that two-month period. Prior to the most recent bimonthly count, citations to the report have accrued as follows, as tracked by Essential Science Indicators Hot Papers:

September-October 2013: 9 citations
July-August 2013: 5
May-June 2013: 4
March-April 2013: 5
January-February 2013: 5
November-December 2012: 2
September-October 2012: 1
July-August 2012: 1

Total citations to date: 45

SOURCE: Thomson Reuters Web of Science

The data and citation records included in this report are from Thomson Reuters Web of ScienceTM. Web of ScienceTM is a registered trademark of Thomson Reuters. All rights reserved.