ScienceWatch.com, September 2010

Tracking Trends and Performance in Global Research Since 1989


Role of Soluble Amyloid-ß Examined in Alzheimer’s

Recent research in Alzheimer’s disease has shifted from emphasis on plaques and tangles of beta-amyloid protein in the brains of Alzheimer’s patients to smaller, soluble forms of beta-amyloid. Soluble forms of human beta-amyloid have been observed to interfere with the memory of learned behavior in rats. Soluble beta-amyloid also correlates well with dementia in human patients. These findings open a promising area for further Alzheimer’s research.
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Nicolas C. PolferNicolas C. Polfer on Infrared Spectroscopy of Ions

From the interview: "Developments in laser technology have now made it possible to also record the infrared spectra of ions in a mass spectrometer. The combination of ultra-high sensitivity (from mass spectrometry) and high structural information (from laser spectroscopy) are particularly useful for answering questions in biomolecular sciences..."
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SCI-BYTES: Week of September 5, 2010

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Featured image: Combination of two brain diagrams in one for comparison. In the left normal brain, in the right brain of a person with Alzheimer's disease. Image from the Wiki Commons.