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Robert Freedman talks with ScienceWatch.com and answers a few questions about this month's New Hot Paper in the field of Psychiatry/Psychology.
Robert Freedman Article Title: Initial phase 2 trial of a nicotinic agonist in schizophrenia
Authors: Freedman, R;Olincy, A;Buchanan, RW;Harris, JG;Gold, JM;Johnson, L;Allensworth, D;Guzman-Bonilla, A;Clement, B;Ball, MP;Kutnick, J;Pender, V;Martin, LF;Stevens, KE;Wagner, BD;Zerbe, GO;Soti, F;Kem, WR
Journal: AMER J PSYCHIAT
Volume: 165, Issue: 8, Page: 1040-1047, Year: AUG 2008
* Univ Colorado, Hlth Sci Ctr, Dept Psychiat C249 32, Denver, CO 80262 USA.
* Denver VA Med Ctr, Dept Psychiat, Denver, CO USA.
(addresses have been truncated)

 Why do you think your paper is highly cited?

The targeting of nicotinic receptors for therapeutic treatment of mental disorders is an emerging field of translational research. A long history of basic inquiry into this mechanism of neurotransmission is now being used to devise new treatment possibilities for patients.

 Where do you see your research leading in the future?

The future of psychiatric treatment involves translating basic research in neurobiology into new therapeutic strategies. As Editor of the American Journal of Psychiatry, where this paper was published, I believe that journals should disseminate the results of early therapeutic investigations to encourage other investigators to undertake similar translational studies.

Robert Freedman, M.D.
Professor and Chair
Department of Psychiatry
University of Colorado
Denver, Colorado, USA
Web | Web | Web

KEYWORDS: CONSENSUS COGNITIVE BATTERY; ALPHA-BUNGAROTOXIN; NEGATIVE SYMPTOMS; DOUBLE-BLIND; CLOZAPINE; RECEPTORS; RELIABILITY; SMOKING; DEFICIT; GTS-21.

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2009 : November 2009 - New Hot Papers : Bob Freedman on Nicotinic Agonist in Schizophrenia
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