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As part of this bimonthly processing,
ScienceWatch.com selects the Research Fronts with the largest absolute
increase in size in each of the 22 major
fields covered by
Essential Science IndicatorsSM
from Thomson
Reuters. The size of a research front is determined by the number of
core papers it contains. This Research Front on NOVEL DRUG DELIVERY
PLATFORMS WITH DENDRIMERS from the field of Pharmacology & Toxicology was
selected for mapping from the list of Top Topics for June 2008
(data from the first bimonthly period of
2008). The map is a diagrammatic
representation of the 34 core papers comprising the front
in
Pharmacology & Toxicology.
Each circle
represents a highly cited paper whose bibliographic information is displayed
when the user clicks on the circle. The lines between circles represent the
strongest co-citation links for each paper (that is, indicating that the papers
are frequently cited together). Papers close to each other on the map are
generally more highly co-cited. The most recent paper(s) are indicated in pink.

Core Papers
Label: Stiriba-2002 Title: Dendritic polymers in biomedical applications: From potential to clinical use in diagnostics and therapy Journal: ANGEW CHEM INT ED, 41 (8): 1329-1334 2002 Citations: 227 Authors: Stiriba, SE;Frey, H;Haag, R Addresses:
Univ Freiburg, Inst Makromol Chem, Stefan Meier Str 21-31, D-79104 Freiburg, Germany
Univ Freiburg, Inst Makromol Chem, D-79104 Freiburg, Germany
Univ Freiburg, Freiburger Mat Forschungszentrum, FMF, D-79104 Freiburg, Germany
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Label: Boas-2004 Title: Dendrimers in drug research Journal: CHEM SOC REV, 33 (1): 43-63 JAN 10 2004 Citations: 189 Authors: Boas, U;Heegaard, PMH Addresses:
Danish Vet Inst, Dept Immunol & Biochem, Bulowsvej 27, DK-1790 Copenhagen, Denmark
Danish Vet Inst, Dept Immunol & Biochem, DK-1790 Copenhagen, Denmark
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Label: Cloninger-2002 Title: Biological applications of dendrimers Journal: CURR OPIN CHEM BIOL, 6 (6): 742-748 DEC 2002 Citations: 165 Authors: Cloninger, MJ Addresses:
Montana State Univ, Dept Chem & Biochem, 108 Gaines Hall, Bozeman, MT 59717 USA
Montana State Univ, Dept Chem & Biochem, Bozeman, MT 59717 USA
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Label: Patri-2002 Title: Dendritic polymer macromolecular carriers for drug delivery Journal: CURR OPIN CHEM BIOL, 6 (4): 466-471 AUG 2002 Citations: 135 Authors: Patri, AK;Majoros, IJ;Baker, JR Addresses:
Univ Michigan, Dept Internal Med, Ctr Biol Nanotechnol, 9220C MSRB 3,1150 W Med Ctr Dr, Ann Arbor, MI 48109 USA
Univ Michigan, Dept Internal Med, Ctr Biol Nanotechnol, Ann Arbor, MI 48109 USA
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Label: Quintana-2002 Title: Design and function of a dendrimer-based therapeutic nanodevice targeted to tumor cells through the folate receptor Journal: PHARMACEUT RES, 19 (9): 1310-1316 SEP 2002 Citations: 135 Authors: Quintana, A;Raczka, E;Piehler, L;Lee, I;Myc, A;Majoros, I;Patri, AK;Thomas, T;Mule, J;Baker, JR Addresses:
Univ Michigan, Sch Med, Dept Internal Med, Ctr Biol Nanotechnol, Ann Arbor, MI 48109 USA
Univ Michigan, Sch Med, Dept Internal Med, Ctr Biol Nanotechnol, Ann Arbor, MI 48109 USA
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Label: Lee-2005 Title: Designing dendrimers for biological applications Journal: NAT BIOTECHNOL, 23 (12): 1517-1526 DEC 2005 Citations: 109 Authors: Lee, CC;MacKay, JA;Frechet, JMJ;Szoka, FC Addresses:
Univ Calif San Francisco, Dept Biopharmaceut Sci & Pharmaceut Chem, San Francisco, CA 94143 USA
Univ Calif San Francisco, Dept Biopharmaceut Sci & Pharmaceut Chem, San Francisco, CA 94143 USA
Univ Calif Berkeley, Dept Chem, Berkeley, CA 94720 USA
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Label: Gillies-2005 Title: Dendrimers and dendritic polymers in drug delivery Journal: DRUG DISCOV TODAY, 10 (1): 35-43 JAN 1 2005 Citations: 103 Authors: Gillies, ER;Frechet, JMJ Addresses:
Univ Calif Berkeley, Dept Chem, Berkeley, CA 94720 USA
Univ Calif Berkeley, Dept Chem, Berkeley, CA 94720 USA
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Label: Luo-2002 Title: Poly(ethylene glycol)-conjugated PAMAM dendrimer for biocompatible, high-efficiency DNA delivery Journal: MACROMOLECULES, 35 (9): 3456-3462 APR 23 2002 Citations: 103 Authors: Luo, D;Haverstick, K;Belcheva, N;Han, E;Saltzman, WM Addresses:
Cornell Univ, Sch Chem Engn, 120 Olin Hall, Ithaca, NY 14850 USA
Cornell Univ, Sch Chem Engn, Ithaca, NY 14850 USA
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Label: Aulenta-2003 Title: Dendrimers: a new class of nanoscopic containers and delivery devices Journal: EUR POLYM J, 39 (9): 1741-1771 SEP 2003 Citations: 99 Authors: Aulenta, F;Hayes, W;Rannard, S Addresses:
Univ Reading, Sch Chem, Reading RG6 6AH, Berks, England
Univ Reading, Sch Chem, Reading RG6 6AH, Berks, England
Unilever Res & Dev, Wirral CH63 3JW, Merseyside, England
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Label: Ihre-2002 Title: Polyester dendritic systems for drug delivery applications: Design, synthesis, and characterization Journal: BIOCONJUGATE CHEMISTRY, 13 (3): 443-452 MAY-JUN 2002 Citations: 97 Authors: Ihre, HR;De Jesus, OLP;Szoka, FC;Frechet, JMJ Addresses:
Univ Calif Berkeley, Dept Chem, Berkeley, CA 94720 USA
Univ Calif Berkeley, Dept Chem, Berkeley, CA 94720 USA
Univ Calif San Francisco, Sch Pharm, San Francisco, CA 94143 USA
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Label: DeJesus-2002 Title: Polyester dendritic systems for drug delivery applications: In vitro and in vivo evaluation Journal: BIOCONJUGATE CHEMISTRY, 13 (3): 453-461 MAY-JUN 2002 Citations: 94 Authors: De Jesus, OLP;Ihre, HR;Gagne, L;Frechet, JMJ;Szoka, FC Addresses:
Univ Calif Berkeley, Dept Chem, Berkeley, CA 94720 USA
Univ Calif Berkeley, Dept Chem, Berkeley, CA 94720 USA
Univ Calif San Francisco, Sch Pharm, San Francisco, CA 94143 USA
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Label: Kukowska-Latallo-2005 Title: Nanoparticle targeting of anticancer drug improves therapeutic response in animal model of human epithelial cancer Journal: CANCER RES, 65 (12): 5317-5324 JUN 15 2005 Citations: 76 Authors: Kukowska-Latallo, JF;Candido, KA;Cao, ZY;Nigavekar, SS;Majoros, IJ;Thomas, TP;Balogh, LP;Khan, MK;Baker, JR Addresses:
Univ Michigan, Hlth Syst, Ctr Biol Nanotechnol, 1150 W Med Ctr Dr,9220 MSRB3, Ann Arbor, MI 48109 USA
Univ Michigan, Hlth Syst, Ctr Biol Nanotechnol, Ann Arbor, MI 48109 USA
Univ Michigan, Hlth Syst, Dept Radiat Oncol, Ann Arbor, MI 48109 USA
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Label: Ballauff-2004 Title: Dendrimers in solution: Insight from theory and simulation Journal: ANGEW CHEM INT ED, 43 (23): 2998-3020 2004 Citations: 70 Authors: Ballauff, M;Likos, CN Addresses:
Univ Bayreuth, POB 101251, D-95440 Bayreuth, Germany
Univ Bayreuth, D-95440 Bayreuth, Germany
Univ Dusseldorf, Inst Theoret Phys 2, D-40225 Dusseldorf, Germany
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Label: Caminade-2004 Title: Nanomaterials based on phosphorus dendrimers Journal: ACCOUNT CHEM RES, 37 (6): 341-348 JUN 2004 Citations: 59 Authors: Caminade, AM;Majoral, JP Addresses:
CNRS, Chim Coordinat Lab, 205 Route Narbonne, F-31077 Toulouse 4, France
CNRS, Chim Coordinat Lab, F-31077 Toulouse 4, France
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Label: Dufes-2005 Title: Dendrimers in gene delivery Journal: ADVAN DRUG DELIVERY REV, 57 (15): 2177-2202 DEC 14 2005 Citations: 55 Authors: Dufes, C;Uchegbu, IF;Schatzlein, AG Addresses:
Univ Glasgow, Beatson Labs, Canc Res UK Ctr Oncol & Appl Pharmacol, Glasgow G61 1BD, Lanark, Scotland
Univ Glasgow, Beatson Labs, Canc Res UK Ctr Oncol & Appl Pharmacol, Glasgow G61 1BD, Lanark, Scotland
Univ Strathclyde, Dept Pharmaceut Sci, Glasgow G4 0NR, Lanark, Scotland
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Label: Duncan-2005 Title: Dendrimer biocompatibility and toxicity Journal: ADVAN DRUG DELIVERY REV, 57 (15): 2215-2237 DEC 14 2005 Citations: 50 Authors: Duncan, R;Izzo, L Addresses:
Univ Cardiff Wales, Welsh Sch Pharm, Ctr Polymer Therapeut, Cardiff CF10 3XF, Wales
Univ Cardiff Wales, Welsh Sch Pharm, Ctr Polymer Therapeut, Cardiff CF10 3XF, Wales
Univ Salerno, Dipartimento Chim, I-84081 Baronissi, SA, Italy
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Label: Chase-2004 Title: Where organometallics and dendrimers merge: the incorporation of organometallic species into dendritic molecules Journal: J ORGANOMET CHEM, 689 (24): 4016-4054 Sp. Iss. SI NOV 29 2004 Citations: 49 Authors: Chase, PA;Gebbink, RJMK;van Koten, G Addresses:
Univ Utrecht, Debye Inst, Dept Met Mediated Synth, Padualaan 8, NL-3584 CH Utrecht, Netherlands
Univ Utrecht, Debye Inst, Dept Met Mediated Synth, NL-3584 CH Utrecht, Netherlands
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Label: Majoros-2006 Title: PAMAM dendrimer-based multifunctional conjugate for cancer therapy: Synthesis, characterization, and functionality Journal: BIOMACROMOLECULES, 7 (2): 572-579 FEB 2006 Citations: 48 Authors: Majoros, IJ;Myc, A;Thomas, T;Mehta, CB;Baker, JR Addresses:
Univ Michigan, Michigan Nanotechnol Inst Med & Biol Sci, 200 Zina Pitcher Pl,4027 Kresge 2, Ann Arbor, MI 48109 USA
Univ Michigan, Michigan Nanotechnol Inst Med & Biol Sci, Ann Arbor, MI 48109 USA
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Label: Delort-2004 Title: A strong positive dendritic effect in a peptide dendrimer-catalyzed ester hydrolysis reaction Journal: J AM CHEM SOC, 126 (48): 15642-15643 DEC 8 2004 Citations: 43 Authors: Delort, E;Darbre, T;Reymond, JL Addresses:
Univ Bern, Dept Chem & Biochem, Freiestr 3, CH-3012 Bern, Switzerland
Univ Bern, Dept Chem & Biochem, CH-3012 Bern, Switzerland
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Label: Maiti-2005 Title: Effect of solvent and pH on the structure of PAMAM dendrimers Journal: MACROMOLECULES, 38 (3): 979-991 FEB 8 2005 Citations: 41 Authors: Maiti, PK;Cagin, T;Lin, ST;Goddard, WA Addresses:
CALTECH, Mat & Proc Simulat Ctr, Pasadena, CA 91125 USA
CALTECH, Mat & Proc Simulat Ctr, Pasadena, CA 91125 USA
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Label: Kobayashi-2005 Title: Nano-sized MRI contrast agents with dendrimer cores Journal: ADVAN DRUG DELIVERY REV, 57 (15): 2271-2286 DEC 14 2005 Citations: 38 Authors: Kobayashi, H;Brechbiel, MW Addresses:
NCI, Mol Imaging Program, Ctr Canc Res, NIH, Bldg 10,Room 1B40,10 Ctr Dr, Bethesda, MD 20892 USA
NCI, Mol Imaging Program, Ctr Canc Res, NIH, Bethesda, MD 20892 USA
NCI, Radiat Oncol Branch, Canc Res Ctr, NIH, Bethesda, MD 20892 USA
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Label: Patri-2005 Title: Targeted drug delivery with dendrimers: Comparison of the release kinetics of covalently conjugated drug and non-covalent drug inclusion complex Journal: ADVAN DRUG DELIVERY REV, 57 (15): 2203-2214 DEC 14 2005 Citations: 34 Authors: Patri, AK;Kukowska-Latallo, JF;Baker, JR Addresses:
Nanotechnol Inst Med & Biol Sci, Div Clin Immunol & Allergy, Dept Internal Med, 9220 MSRB III, Ann Arbor, MI 48109 USA
Univ Michigan, Hlth Syst, Michigan Nanotechnol Inst Med & Biol Sci, Ann Arbor, MI 48109 USA
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Label: D'Emanuele-2005 Title: Dendrimer-drug interactions Journal: ADVAN DRUG DELIVERY REV, 57 (15): 2147-2162 DEC 14 2005 Citations: 27 Authors: D'Emanuele, A;Attwood, D Addresses:
Univ Manchester, Sch Pharm & Pharmaceut Sci, Oxford Rd, Manchester M13 9PL, Lancs, England
Univ Manchester, Sch Pharm & Pharmaceut Sci, Manchester M13 9PL, Lancs, England
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Label: Talanov-2006 Title: Dendrimer-based nanoprobe for dual modality magnetic resonance and fluorescence imaging Journal: NANO LETT, 6 (7): 1459-1463 JUL 12 2006 Citations: 26 Authors: Talanov, VS;Regino, CAS;Kobayashi, H;Bernardo, M;Choyke, PL;Brechbiel, MW Addresses:
NCI, Radioimmune & Inorgan Chem Sect, Radiat Oncol Branch, NIH,Mol Imaging Program, Bldg 10,Room 1B40,10 Ctr Dr, Bethesda, MD 20892 USA
NCI, Radioimmune & Inorgan Chem Sect, Radiat Oncol Branch, NIH,Mol Imaging Program, Bethesda, MD 20892 USA
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Label: Qiu-2006 Title: Polymer architecture and drug delivery Journal: PHARMACEUT RES, 23 (1): 1-30 JAN 2006 Citations: 24 Authors: Qiu, LY;Bae, YH Addresses:
Univ Utah, Dept Pharmaceut & Pharmaceut Chem, 421 Wakara Way,Suite 315, Salt Lake City, UT 84108 USA
Univ Utah, Dept Pharmaceut & Pharmaceut Chem, Salt Lake City, UT 84108 USA
Zhejiang Univ, Coll Pharmaceut Sci, Hangzhou 310031, Peoples R China
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Label: Darbre-2006 Title: Peptide dendrimers as artificial enzymes, receptors, and drug-delivery agents Journal: ACCOUNT CHEM RES, 39 (12): 925-934 DEC 19 2006 Citations: 22 Authors: Darbre, T;Reymond, JL Addresses:
Univ Bern, Dept Chem & Biochem, Freiestr 3, CH-3012 Bern, Switzerland
Univ Bern, Dept Chem & Biochem, CH-3012 Bern, Switzerland
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Label: Shabat-2006 Title: Self-immolative dendrimers as novel drug delivery platforms Journal: J POLYM SCI A-POLYM CHEM, 44 (5): 1569-1578 MAR 1 2006 Citations: 22 Authors: Shabat, D Addresses:
Tel Aviv Univ, Raymond & Beverly Sackler Fac Exact Sci, Sch Chem, IL-69978 Tel Aviv, Israel
Tel Aviv Univ, Raymond & Beverly Sackler Fac Exact Sci, Sch Chem, IL-69978 Tel Aviv, Israel
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Label: Yang-2006 Title: Dendrimers for pharmaceutical and biomedical applications Journal: J BIOMATER SCI-POLYM ED, 17 (1-2): 3-19 2006 Citations: 22 Authors: Yang, H;Kao, WYJ Addresses:
Univ Wisconsin, Sch Pharm, 777 Highland Ave, Madison, WI 53705 USA
Univ Wisconsin, Sch Pharm, Madison, WI 53705 USA
Univ Wisconsin, Coll Engn, Dept Biomed Engn, Madison, WI 53705 USA
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Label: Lo-2007 Title: Development of dendrimers: Macromolecules for use in organic light-emitting diodes and solar cells Journal: CHEM REV, 107 (4): 1097-1116 APR 2007 Citations: 11 Authors: Lo, SC;Burn, PL Addresses:
Univ Oxford, Dept Chem, Chem Res Lab, 12 Mansfield Rd, Oxford OX1 3TA, England
Univ Oxford, Dept Chem, Chem Res Lab, Oxford OX1 3TA, England
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Label: Tomalia-2007 Title: Dendrimers as multi-purpose nanodevices for oncology drug delivery and diagnostic imaging Journal: BIOCHEM SOC TRANS, 35: 61-67 Part 1 FEB 2007 Citations: 11 Authors: Tomalia, DA;Reyna, LA;Svenson, S Addresses:
Dendrit Nanotechnol Inc, 2625 Denison Dr, Mt Pleasant, MI 48858 USA
Dendrit Nanotechnol Inc, Mt Pleasant, MI 48858 USA
Cent Michigan Univ, Dept Chem, Mt Pleasant, MI 48859 USA
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Label: Antoni-2007 Title: A chemoselective approach for the accelerated synthesis of well-defined dendritic architectures Journal: CHEM COMMUN, (22): 2249-2251 JUN 14 2007 Citations: 9 Authors: Antoni, P;Nystrom, D;Hawker, CJ;Hult, A;Malkoch, M Addresses:
Royal Inst Technol, Teknikringen S6-58, SE-10044 Stockholm, Sweden
Royal Inst Technol, SE-10044 Stockholm, Sweden
Univ Calif Santa Barbara, Mat Res Lab, Santa Barbara, CA 93106 USA
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Label: Chandrasekar-2007 Title: The development of folate-PAMAM dendrimer conjugates for targeted delivery of anti-arthritic drugs and their pharmacokinetics and biodistribution in arthritic rats Journal: BIOMATERIALS, 28 (3): 504-512 JAN 2007 Citations: 8 Authors: Chandrasekar, D;Sistla, R;Ahmad, FJ;Khar, RK;Diwan, PV Addresses:
Indian Inst Chem Technol, Div Pharmacol, Uppal Rd, Hyderabad 500007, Andhra Pradesh, India
Indian Inst Chem Technol, Div Pharmacol, Hyderabad 500007, Andhra Pradesh, India
Jamia Hamdard Deemed Univ, Fac Pharm, Dept Pharmaceut, New Delhi, India
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Label: Gingras-2007 Title: Cleavable dendrimers Journal: ANGEW CHEM INT ED, 46 (7): 1010-1017 2007 Citations: 8 Authors: Gingras, M;Raimundo, JM;Chabre, YM Addresses:
Univ Nice, Fac Sci, Inst Chem, 28 Av Valrose, F-06108 Nice 2, France
Univ Nice, Fac Sci, Inst Chem, F-06108 Nice 2, France
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Label: Paleos-2007 Title: Molecular engineering of dendritic polymers and their application as drug and gene delivery systems Journal: MOL PHARM, 4 (2): 169-188 MAR-APR 2007 Citations: 8 Authors: Paleos, CM;Tsiourvas, D;Sideratou, Z Addresses:
NCSR Demokritos, Inst Phys Chem, Aghia Paraskevi 15310, Attiki, Greece
NCSR Demokritos, Inst Phys Chem, Aghia Paraskevi 15310, Attiki, Greece
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Keywords: DRUG DELIVERY APPLICATIONS;
TARGETED DRUG DELIVERY; NOVEL DRUG DELIVERY PLATFORMS; ONCOLOGY DRUG DELIVERY;
PAMAM DENDRIMERS.
Top Topics : 2008 : Jun. 08 - NOVEL DRUG DELIVERY PLATFORMS WITH DENDRIMERS - Research Front Map
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